周洁心1，敬 璞1*，舒邦金2，兰余2，冯华芳2，曹晓念2*
（1.上海交通大学农业与生物学院,上海 200240; 2.泸州老窖股份有限公司,泸州 646000）
摘要：本文研究了以红参/白参为主要原料的养生酒对小鼠免疫功能的调节作用。结果显示红/白参养生酒对小鼠免疫器官指数、腹腔巨噬细胞吞噬能力和迟发型变态反应没有显著影响（P＞0.05）。而白参高浓度养生酒和红参低浓度养生酒组的NK杀伤能力均显著高于基酒组（P＜0.05）；红参养生酒组的淋巴细胞增殖能力均显著高于基酒组（P＜0.05）。在体液免疫实验中，红参高浓度养生酒组的抗体生成和血清溶血素水平均低于红参低浓度组的。红参低浓度（45 mg/mL）养生酒具有调节免疫功能的作用。
关键词：人参；养生酒；免疫调节
中图分类号：TS218.2 文献标识码：A 文章编号：1674-506X（2024）01-0093-0006
Immunomodulatory Effects of Ginseng Healthcare Liqueur on Mice
ZHOU Jiexin1, JING Pu1*, SHU Bangjin2, LAN Yu2, FENG Huafang2, CAO Xiaoniao2*
(1.School of Agriculture and Biology,Shanghai Jiaotong University,Shanghai 200240,China;
2.Luzhou Laojiao Co., Ltd., Luzhou 646000,China）
Abstract: This research studied the immunomodulatory effects of healthcare liqueur with red/white ginseng as the primary raw material. Results showed that red/white ginseng healthcare liqueur had no significant effect on immune organ index,peritoneal macrophage phagocytosis and delayed allergic reaction of mice (P>0.05).While the NK killing ability of the high concentration-white ginseng healthcare liqueur,and low concentrationred ginseng healthcare liqueur groups were significantly higher than that of the base liqueur group (P<0.05);the lymphocyte proliferation ability of both low and high concentration- red ginseng healthcare liqueur groups were significantly higher than that of the base liqueur group (P<0.05). In the humoral immunity tests,the antibody production and serum hemolysin level of high concentration-red ginseng healthcare liqueur group were lower than those in low concentration-red ginseng healthcare liqueur group. In conclusion,the low concentrationred ginseng healthcare liqueur (45 mg/mL)has immune regulation effect.
Keywords: ginseng; healthcare liqueur; immunomodulatory
Doi: 10.3969/j.issn.1674-506X.2024.01-015
收稿日期：2023-03-14
基金项目：滋味大曲品质提升及免疫调节功能评价研究
作者简介：周洁心（1995-），女，硕士。研究方向：食品功能与营养。
*通信作者：敬璞（1972-），女，博士，教授。研究方向：天然植物功能成分研究及加工技术；曹晓念（1986-），女，高级工程师。研究方向：酿造食品开发、风味营养、生理健康机理研究。
引用格式:周洁心,敬璞,舒邦金,等.人参养生酒对小鼠免疫功能调节作用的研究[J].食品与发酵科技,2024,60(1):93-98.
